You are here: Research > UK funded projects
Current UK funded projects

Current UK funded projects

Below you will find information about current UK funded research projects. For more information on international EB research visit DEBRA International.

Akker, DEBRA Clinical Research Fellow (Dundee) - Development of Novel Gene Technology for Treating Epidermolysis Bullosa Simplex

Bauer 5 (Austria, Italy, Germany) – To develop therapies which combine ex vivo gene therapy with stem cell transplantation for Junctional EB

Brunton 1 (Edinburgh) – Defining the role of kindlin-1 in the regulation of microtubule stability and mitosis

Inman-South 1 (Dundee) – TGFβ signalling in RDEB Squamous Cell Carcinoma

Gaggioli 2 (Nice, France) – To validate findings that will develop a drug to counteract scarring and Squamous Cell Carcinoma in patients with Recessive Dystrophic EB

Mellerio 1 (London) – To document a Natural History of EB and validate Clinical Endpoints appropriate to therapy evaluation by industry and regulatory authorities

Roopenian 2 (Maine, USA) – To identify modifier genes in Junctional EB that affect the severity of symptoms experienced by different patients with the same primary gene defect

Steinhoff (Dublin) – Epidemiological and Pathophysiological Studies about the Problem of Itch (Pruritus) in Patients with Epidermolysis Bullosa (EB)

Uitto 1 (Philadelphia, USA) – Novel approaches for read-through of nonsense mutations in COL7A1

Smaller grants funded by DEBRA UK:

Hubbard (London) - Longitudinal retrospective study on bone health in adults with RDEB

Hickerson (Dundee) - Development of a Skin Fragility Assessment Tool

Projects funded by the Sohana Research Fund:

ADSTEM (London) – Understanding how allogeneic mesenchymal stromal cells can modify disease severity in RDEB

LENTICOL (London) – A prospective phase I study of lentiviral-mediated COL7A1 gene-corrected autologous fibroblast therapy

Tolar 3 (Minnesota, USA) – Limbal stem-cell therapy for RDEB

Make a difference

Make a difference

£25.00 
A MONTH

Could pay for one hour of research to bring us closer to finding effective treatments for EB.

Donate Today

Get involved

Get involved

There are so many ways you can help DEBRA

MORE DETAILS