DEBRA members Isla and Fazeel, who live with recessive dystrophic epidermolysis bullosa - RDEB.
Isla and Fazeel both live with recessive dystrophic epidermolysis bullosa (RDEB).

A life free of pain is what we all want. Unfortunately for people living with EB, excruciating pain is something they must live with, every day. There is hope though...

DEBRA’s ‘A Life Free of Pain’ appeal aims to raise £5m by the end of 2023 to develop treatments that will enable people to live free from the pain of EB.



How you can help

We need to raise:

  • £3m to accelerate our drug repurposing programme, which will involve testing drugs which already successfully treat other inflammatory skin conditions such as Psoriasis and Atopic Dermatitis. These drugs are already available within the NHS, and we believe they could be effective in slowing, stopping, or reversing, the progression of EB.
  • £1m to fund life-changing treatments including eye lubricants, oral sprays, and topical treatments that are applied to wounds, all of which could radically improve quality of life for people living with EB.
  • £1m to enable DEBRA to continue to provide EB community support and healthcare whilst we seek effective treatments. 

Any donation makes a difference and will get us one step closer to a world where no one has to suffer with the pain of EB.