Epidermolysis Bullosa is a spectrum of diseases with symptoms that can be different from one person to the next. 

Different types of EB can be caused by changes in the genes for skin proteins like keratin and collagen. Within each type, symptoms can be more or less extreme and there are quite a few named sub-types of EB where a slightly different set of symptoms have been described by a researcher.

EB simplex 

EBS 

70% of EB cases 

Keratin 

(Keratin-5 and Keratin-14) 

Epidermolysis bullosa simplex | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program (nih.gov) 

Dystrophic EB 

DEB 

25% of EB cases 

Collagen 

(Collagen -7) 

Dystrophic epidermolysis bullosa | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program (nih.gov) 

Junctional EB 

JEB 

5% of EB cases 

Laminin or collagen-17 

Junctional epidermolysis bullosa | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program (nih.gov) 

Kindler EB 

KEB 

Less than 1% of EB cases 

Kindlin-1 

Kindler syndrome | Genetic and Rare Diseases Information Center (GARD) – an NCATS Program (nih.gov) 


This animation explains a bit about Epidermolysis Bullosa (EB) at the molecular level.
The Genetic Alliance UK website provides information about genetic conditions in general.