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  1. EB support
  2. About EB

About EB

Find out more about the painful genetic skin blistering condition, epidermolysis bullosa (EB). The four main types along with symptoms and support options are listed below. 

What is EB?

What is EB?

Epidermolysis bullosa (EB) is a painful genetic skin blistering condition with no cure. Find out about different types of EB, causes, symptoms and treatments. Read more

Published: 1st July, 2020

Updated: 26th October, 2023

Author: Wendy Garstin

Testing & diagnosis

Testing & diagnosis

Laboratory diagnosis is essential to determine the type of EB and the precise cause at the genetic (DNA) and protein levels, but other diagnostic tools are also available. Read more

Published: 2nd July, 2020

Updated: 8th June, 2023

Author:

EB simplex (EBS)

EB simplex (EBS)

The most common and mild-moderate form of EB whereby the defective gene and fragility occurs within the upper layer of the skin – the epidermis. Read more

Published: 3rd July, 2020

Updated: 8th June, 2023

Author:

Dystrophic EB (DEB)

Dystrophic EB (DEB)

Can be mild or severe (dominant or recessive). The defective gene and fragility occurs below the basement membrane within the superficial dermis. Read more

Published: 10th July, 2020

Updated: 8th June, 2023

Author:

Junctional EB (JEB)

Junctional EB (JEB)

A moderate-severe form of EB. The defective gene and fragility occurs in the basement membrane - the structure that keeps the epidermis and dermis together. Read more

Published: 15th July, 2020

Updated: 8th June, 2023

Author:

Kindler EB (KEB)

Kindler EB (KEB)

Named after the protein Kindlin1, which is the protein affected by the defective gene. This type of EB is very rare but fragility can occur at multiple levels of the skin. Read more

Published: 20th July, 2020

Updated: 8th June, 2023

Author:

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Latest

  • DEBRA raises £5 million to help stop the pain of EB

    DEBRA raises £5 million to help stop the pain of EB

    We're delighted to share with you the news that since we launched DEBRA’s A Life Free of Pain appeal, we have raised over £5m to help stop the pain of EB.

  • How and why had this condition suddenly invaded my family without warning?

    How and why had this condition suddenly invaded my family without warning?

    I had never heard of EB before and I naively thought the blisters which were appearing on Georgia’s tiny body would heal - but when a doctor explained the full extent of EB to me I found the horror difficult to comprehend.

  • Parent Pitstop: March 2024

    Parent Pitstop: March 2024

    Parent Pitstops are an opportunity to connect with other members online. We will update this page with more details about our March event soon.

  • Parent Pitstop: January 2024

    Parent Pitstop: January 2024

    Parent Pitstops are an opportunity to connect with other members online. We will update this page with more details about our January event soon.

Most read

  • Find a store

    Find a store

    Find your nearest DEBRA charity shop and help fight EB. Our stores sell affordable and quality pre-loved clothing, furniture, electrical items, books, homeware and more.

  • Furniture collection

    Furniture collection

    Donate your unwanted furniture, homewares and electrical items using our free furniture collection service. With safety measures in place, donating your items couldn’t be easier.

  • Items we do not sell

    Find out what health and safety standards and labels we require and which items we cannot sell.

  • Graeme Souness swimming the English Channel  to raise £1.1m to stop the pain of EB

    Graeme Souness swimming the English Channel to raise £1.1m to stop the pain of EB

    Graeme Souness, ex-international footballer, manager, and pundit, is swimming the English Channel this June to raise £1.1m to stop the pain of epidermolysis bullosa (EB).

  • What is EB?

    What is EB?

    Epidermolysis bullosa (EB) is a painful genetic skin blistering condition with no cure. Find out about different types of EB, causes, symptoms and treatments.

  • Contact Us

  • Donate items

    Donate items

    Donate your quality pre-loved items, including clothes, furniture and homeware to keep them from landfill and help us to raise vital funds through our stores. Find out more about how to donate items today.

  • Work with us

    Work with us

    DEBRA can only continue its vital work with the support and encouragement of the local community and with the hard work of its employees and volunteers.

  • Imagine your skin being in constant pain? No one should have to live like this

    Imagine your skin being in constant pain? No one should have to live like this

    Imagine a dozen surgeries in less than a decade? No one should have to live like this. Please help us find treatments to #StopThePain.

  • Become a member

    Become a member

    If you or a family member live with EB, are a carer or someone who works with people affected by EB, then you can become a DEBRA member. Find out how.

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Alternatively, become a member to receive information tailored for people living and working with EB. 

 

 

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